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Wednesday, 28 November 2007

Novel Luciferase Assay System for HTS Applications

Targeting Systems Offers a Novel Luciferase Assay System for HTS Applications
This product is based on gaussia luciferase, a secreted luciferase that is more than a 1000 times brighter than firefly or renilla luciferases. When it comes to screening compounds that affect the activity of a weak promoter, an assay type and readout method can make the difference between actually finding compounds or proteins of interest and not finding them. Gaussia luciferase is extremely attractive for drug screening involving weak promoters. Ease of use, elimination of cell lysis, signal stability, and high signal intensity make the Secreted Gaussia Luciferase System a powerful tool for high-throughput applications. Targeting Systems also offers a dual luciferase reporter system based on gaussia luciferase with firefly luciferase as the second reporter.
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