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Monday 3 December 2007

Human Retinol-binding Protein 4 QuantikineR ELISA

Human Retinol-binding Protein 4 Quantikine(r) ELISA
R&D Systems now offers a human Retinol-binding Protein 4 (RBP4)
Quantikine ELISA (Catalog # DRB400 ). RBP4 binds to and transports
retinol (vitamin A) from the liver to the peripheral tissues. RBP4 also
promotes hyperglycemia through downregulation of the glucose transporter
GLUT4 in adipocytes, the upregulation of the hepatic gluconeogenic
enzyme PEPCK, and the attenuation of insulin receptor signaling in
skeletal muscle. Serum RBP4 levels are also reported elevated in type 2
diabetes and obesity. This new ELISA is designed to measure RBP4
concentrations in cell culture supernatant, serum, plasma, urine, and
saliva. For more information, please visit www.rndsystems.com or call
1-800-343-7475.

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